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9
Sep
2020
Vaccine Maker Halts Trial Following Unexplained Illness in Volunteer
WEDNESDAY, Sept. 9, 2020 (Healthday News) -- Final testing of a leading coronavirus vaccine candidate was paused by drugmaker AstraZeneca on Tuesday after a trial volunteer experienced a serious adverse reaction. The company did not release specifics on the case, but whether the reaction was caused by the vaccine or was coincidental is still unclear, The New York Times reported. The pause, first reported by STAT, will allow for a safety review and investigation of what caused the illness. The disappointing news came as drug companies around the world race to develop a coronavirus vaccine that could bring an end to an international pandemic that has claimed almost 900,000 lives, the Times reported. AstraZeneca's vaccine is a front-runner, with late-stage clinical trials underway in...
Early Treatment of Rheumatoid Arthritis May Thwart Heart...
8 September 2020
TUESDAY, Sept. 8, 2020 (HealthDay News) -- Starting drug treatment early in rheumatoid arthritis patients may reduce their risk of heart disease, a new study suggests. Rheumatoid arthritis at least doubles the risk of heart disease due to its links with atherosclerosis (plaque buildup in the arteries), heart failure and stroke. The new U.K. study found a link between early rheumatoid arthritis treatment and improvements in vascular stiffness (a gradual loss of elasticity that's an early sign of heart disease). "Our research shows that even at the earliest stages of rheumatoid arthritis, there is increased vascular stiffness in people with no or minimal traditional CVD [cardiovascular disease] risk factors, such as hypertension, high cholesterol or smoking," study co-leader Sven...
COVID-19 Is Tougher on Older Men, and Scientists May Now...
8 September 2020
TUESDAY, Sept. 8, 2020 (HealthDay News) -- Key differences in immune system function may help determine why severe, life-threatening COVID-19 tends to target older men, scientists say. A new study found that among elderly people and in men, especially, certain factors may lead to a weaker immune system response against infection with SARS-CoV-2, the virus that causes COVID-19. That could help explain high rates of intensive care unit admission and death among these patients. "Host responses to SARS-CoV-2 are dependent on viral load and infection time, with observed differences due to age and sex that may contribute to disease severity," said a team led by Nicole Lieberman and Alexander Greninger, both of the University of Washington School of Medicine, in Seattle. In the study, the...
First Trial of Gene-Targeted Asthma Rx in Kids Shows Promise
8 September 2020
TUESDAY, Sept. 8, 2020 (HealthDay News) -- Asthma treatments tailored to the genes of kids and teens could help improve control of their symptoms, new research suggests. The study included 241 adolescents, aged 12 to 18, who were randomly selected to receive either traditional asthma treatment or "personalized medicine" -- treatment based on their individual genetics. During a year of follow-up, those in the personalized medicine group who had a genetic difference in a receptor gene targeted by asthma treatments reported a better quality-of-life score. The score was based on their symptoms, whether their normal activities were limited by their asthma, and how their asthma made them feel. While more research is needed, the findings suggest personalized treatment could better control...
Struggling With CPAP for Sleep Apnea? Surgery May Help
8 September 2020
TUESDAY, Sept. 8, 2020 (HealthDay News) -- Continuous positive airway pressure (CPAP) may be the go-to treatment for sleep apnea, but many people struggle to use it every night. For those who cannot tolerate CPAP, new research finds that a combination of surgical techniques may bring relief. The "multilevel" treatment includes removing the tonsils, repositioning the palate (roof of the mouth) and using radiofrequency to slightly reduce the size of the tongue. In combination, these procedures open up the airway and reduce breathing obstruction, the researchers said. The study found that the multilevel surgery technique reduced the number of times people stopped breathing (apnea events) during sleep and improved daytime sleepiness. People also reported better quality of life after...
Could Antibiotics Make Breast Milk Less Healthy for Babies?
8 September 2020
TUESDAY, Sept. 8, 2020 (HealthDay News) -- Mom's breast milk can be altered by antibiotics in ways that might harm an infant's health, according to a new study. The Canadian researchers were particularly concerned with an increase in bacteria that can be harmful, namely a bacterium called Pseudomonas that can cause a serious intestinal infection called necrotizing enterocolitis in a preterm infant. About 7% of preterm infants develop this frequently fatal condition, in which part of the bowel dies. Also, a class of antibiotics called cephalosporins had a significant dampening effect on the diversity of microbiota in breast milk, the researchers noted. "The bacteria in breast milk has the potential to transfer to a preterm infant's gut and shape their short- and long-term health and...
Why Do Black Men Still Fare Worse With Prostate Cancer?
8 September 2020
TUESDAY, Sept. 8, 2020 (HealthDay News) -- New research reveals what may be fueling racial disparities in U.S. prostate cancer deaths -- disparities that have black patients dying at higher rates than whites. What are they? Education, income and insurance. "Socioeconomic status and insurance status are all changeable factors. Unfortunately, the socioeconomic status inequality in the United States has continued to increase over the past decades," said study author Dr. Wanqing Wen, from Vanderbilt University's School of Medicine in Nashville, Tenn. Wen and his team analyzed U.S. National Cancer Database data on men with prostate cancer who had their prostate removed between 2001 and 2014. The analysis included more than 432,000 whites, more than 63,000 Blacks, nearly 9,000...
Almost 14 Million U.S. Adults Vape, With Use Rising Fastest in Young
8 September 2020
TUESDAY, Sept. 8, 2020 (HealthDay News) -- The number of Americans using electronic cigarettes is soaring, especially among youth, a new study finds. Nearly 14 million U.S. adults vaped in 2018, up from just over 11 million adults in 2016. The increase was seen in all socioeconomic groups, the researchers found. "An increasing number of individuals are using e-cigarettes, especially in the younger age groups, which suggests that more individuals are becoming addicted to e-cigarettes rather than just experimenting with them, making the increased uptake among tobacco-naive individuals even more concerning," said lead researcher Dr. Olufunmilayo Obisesan. She's a postdoctoral fellow at Johns Hopkins Ciccarone Center for the Prevention of Cardiovascular Disease, in Baltimore. "The...
AHA News: Immune-Boosting Cancer Treatment May Pose...
TUESDAY, Sept. 8, 2020 (American Heart Association News) -- A type of cancer treatment used to boost the body's immune system may worsen inflammation in the arteries that distribute blood from the...
AHA News: A Clean Bill of Health at Birth, His Heart...
TUESDAY, Sept. 8, 2020 (American Heart Association News) -- Like many first-time moms, Stephanie Tawata was anxiously navigating the ups and downs of a newborn. She was grateful that her son,...
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