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29
Mar
2022
FDA Reviewers Give Thumbs Down to New ALS Drug
TUESDAY, March 29, 2022 (HealthDay News) -- Despite months of intense lobbying by patient advocates, federal health officials on Monday posted a largely negative review of an experimental drug for the devastating illness known as amyotrophic lateral sclerosis (ALS).In an analysis of Amylyx Pharmaceuticals' drug, known for now only as AMX3005, regulators from the U.S. Food and Drug Administration said the results were “not persuasive.†They pointed to missing data, mistakes in enlisting patients and other problems. Meanwhile, the drug only modestly slowed the disease’s progression in a 137-patient, mid-stage study. An FDA advisory committee is set to meet Wednesday to consider Amylyx's request to skip the typically required phase 3 clinical trial and approve its drug based on the...
Mom's Use of Workplace Disinfectants in Pregnancy Tied...
29 March 2022
TUESDAY, March 29, 2022 (HealthDay News) -- If you're a worker who plans to get pregnant, take heed of a new study that warns that pregnant women who work in hospitals and are exposed to disinfectants may be more likely to have children who suffer from asthma and eczema.The Japanese researchers focused on occupational disinfectant use, noted study author Dr. Reiji Kojima, not use of disinfectants by the general public. "The study found that occupational disinfectant use during pregnancy increased the risk of developing asthma and eczema in children. However, this result still needs to be validated with regard to impact of disinfectant use in general," said Kojima, who is in the University of Yamanashi School of Medicine's department of health sciences. "There is a clear benefit of...
Cancer Patients Vulnerable to Depression, Suicide
29 March 2022
TUESDAY, March 29, 2022 (HealthDay News) -- Cancer can be a devastating diagnosis, and now two new studies show these patients are at increased risk for anxiety, depression and suicide.The findings highlight the need for oncologists to pay more attention to their patients' mental health needs, the authors said.In the first paper, researchers reviewed 28 studies that included more than 22 million cancer patients worldwide and found that they had an 85% higher suicide rate than the general population.The lowest suicide rates were among patients with the best chances of good outcomes -- such as those with prostate, non-metastatic melanoma and testicular cancers -- while the highest suicide rates were among patients with the worst prognoses, like pancreatic and stomach cancers.Cancer...
COVID Can Leave People With Lingering Nerve Damage
29 March 2022
TUESDAY, March 29, 2022 (HealthDay News) -- For many people, damage from COVID-19 continues well beyond the initial infection. A case in point: Pain, tingling and numbness in the hands and feet can occur for weeks or months afterward, a new study reveals.The researchers surveyed more than 1,550 patients who underwent COVID-19 testing at the Washington University Medical Campus in St. Louis over a 10-month period early in the pandemic. Those who tested positive (542) were about three times more likely to report pain, numbness or tingling in their hands and feet (peripheral neuropathy) than those who tested negative, according to the study. "We found that nearly 30% of patients who tested positive for COVID-19 also reported neuropathy problems at the time of their diagnosis," said study...
More Balmy Summer Nights, Higher Heart Death Rate in Men
29 March 2022
TUESDAY, March 29, 2022 (HealthDay News) -- Warm summer nights may leave you tossing and turning in bed, but that could be the least of your worries. Just a slight rise in summer nighttime temperatures increases the risk of heart-related death for men in their 60s, a new study shows."Considering the growing likelihood of extreme summers in Western USA and the United Kingdom, our results invite preventive population health initiatives and novel urban policies aimed at reducing future risk of cardiovascular disease events," the authors wrote in the report published online March 28 in the BMJ Open.For the study, the researchers analyzed data on nearly 40,000 heart-related deaths of men and women that occurred in England and Wales in June and July between 2001 and 2015. They also reviewed...
Depression Raises Stroke Risk for Heart Attack Survivors
29 March 2022
TUESDAY, March 29, 2022 (HealthDay News) -- Heart attack survivors with depression have an increased risk of stroke, and more research is needed to find out why, according to the authors of a new study."There could be a multitude of depression-related factors that are leading to these outcomes," said lead author Frank Annie, a research scientist at Charleston Area Medical Center in West Virginia. "What we're seeing in this data is very troubling, and we need to dig deeper to understand the causes and effects."His team's analysis of data on more than 495,000 U.S. patients who suffered a heart attack between 2015 and 2021 showed that about 51,000 (10.5%) of them were diagnosed with depression afterward.Stroke rates were 12% among those with depression and 8.3% among those without...
'Live' Type of Flu Shot Is Safe for Kids With Asthma: Study
28 March 2022
MONDAY, March 28, 2022 (HealthDay News) -- Yearly flu shots are especially important for kids with asthma as any virus can trigger an asthma attack. But in the not-too-distant future, these kids might be able to get a spritz instead of a jab, new research hints.Current recommendations suggest children with asthma get an inactivated flu shot (the flu virus is dead) instead of the live nasal spray vaccine to avoid wheezing and a potential full-blown asthma attack.However, the latest study shows these kids do just as well with the live nasal mist as the inactivated flu shot, and most kids would gladly choose a nasal mist over a needle."The most important thing we learned is that in this study of children with asthma, including severe asthma, the intranasal vaccine (FluMist) did not lead...
AHA News: Undiagnosed Heart Disease May Be Common in People With Heart Attacks Not Caused by Clots
28 March 2022
MONDAY, March 28, 2022 (American Heart Association News) -- More than two-thirds of people who have a type of heart attack not caused by a blood clot also may have undiagnosed heart disease, according to a small study from Scotland.The study, published Monday in the American Heart Association journal Circulation, focused on people who had what's known as Type 2 heart attacks, which result from strain caused by an illness such as infections or fast heart rates that can lower blood pressure or oxygen in the blood. But when researchers conducted advanced heart imaging, they discovered study participants also had conditions such as narrowed arteries or weakened heart muscles that were frequently undiagnosed. Fewer than a third of those patients were being treated for heart disease."This is...
AHA News: 5-Year-Old With Rare Heart Defect Loves...
MONDAY, March 28, 2022 (American Heart Association News) -- Stephanie Johnson waited in her hospital room for her newborn son, Henry, to return from one last test.Her husband, Tyler, started...
Black, Hispanic Americans Less Likely to Get Bystander CPR
MONDAY, March 28, 2022 (HealthDay News) -- If you collapse in a public place from a cardiac arrest, your chances of receiving lifesaving cardiopulmonary resuscitation (CPR) are substantially...
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